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Spider-Man's first encounter with his deadliest foe leaps off the page like never before! The lethal Venom looks a lot like Spidey's black costume - only bigger, stronger and with a killer smile! Worse still, thanks to the symbiotic suit, Eddie Brock knows all of Peter Parker's secrets! Venom has already terrorized Mary Jane - so it's just a matter of time before he comes face-to-face with Spidey. And Eddie knows just the right place to battle the wall-crawler! Can Peter figure out a way to survive? And if he does, maybe it's time to go back to a more friendly neighborhood outfit! It's one of the greatest issues of David Michelinie and Todd McFarlane's fan-favorite run, with the superstar artist's stunning pages presented for the first time in eye-popping 3D! Reprinting AMAZING SPIDER-MAN (1963) #300.